.4-Aco-dmt is a synthetically produced psychoactive drug and has been suggested to be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin.
Also psilacetin, 4-acetoxy-DMT, or 4-AcO-DMT,O-Acetylpsilocin). It is a synthetically produced psychoactive drug. It is the acetylated form of the psilocybin mushroom. Alkaloid psilocin and is a lower homolog of 4-AcO-DET, 4-AcO-MiPT and 4-AcO-DiPT.
1 Product name 4-Aco-DMT
2 Full chemical name 3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl acetate
3 Formal Name psilacetin, 4-acetoxy-DMT,O-Acetylpsilocin
4 CAS num 92292-84-7
5 Molecular Formula C14H18N2O2
6 Average mass 246.3049 g·mol−1
7 Purity ≥99.0%
8 Stability 2 years
9 Storage -20°C
10 Formulation A powder solid
11 λmax 221, 315 nm
12 Shipping Wet ice in continental US; may vary elsewhere
It is the acetylated form of the psilocybin mushroom alkaloid psilocin. 4-AcO-DET, 4-AcO-MiPT and 4-AcO-DiPT.
The compound has been suggest by David Nichols to be a potentially useful alternative to psilocybin. For pharmacological studies as they are both believe to be prodrugs of psilocin.
Its structural similarities to psilocin and psilocybin results in an identical subjective effect profile. The three compounds can feel indistinguishable from each other.
This allows 4-AcO-DMT to function as a perfect substitute for psilocybin mushrooms.
4-Acetoxy-N,N-dimethyltryptamine (also known as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, and psilacetin) is a novel psychedelic substance of the tryptamine class. 4-AcO-DMT is chemically similar to psilocybin, the active ingredient in psilocybin mushrooms (magic mushrooms). It belongs to a group known as the substituted tryptamines which act by stimulating serotoninreceptors in the brain. SHOP NOW! Buy 4-Aco-DMT Online
In the body O-acetylpsilocin is deacetylated to psilocin by deacetylases/acetyltransferases during first pass metabolism and during subsequent passes through the liver (evident as psilacetin is also active via parenteral routes of ingestion).Claims of subjective differences in effect between the acetylated and non-acetylated forms of psilocin differ: some users report that O-acetylpsilocin lasts slightly longer while others report that it lasts for a considerably shorter time. Many users report less body load and nausea compared to psilocin. Some users find that the visual distortions produced by O-acetylpsilocin more closely resemble those produced by DMT than those produced by psilocin. These differences could be possible if psilocetin is active itself and not merely as a prodrug. Despite this, there have been no controlled clinical studies to distinguish any effects of psilocetin, psilocin, and psilocybin from one another.
O-Acetylpsilocin can be considered an analog of psilocin making it a schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015).A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.buy 4 aco dmt online
O-Acetylpsilocin is ambiguously legal for use as a lab reagent or research chemical; however, it is an acetate ester of psilocin, meaning it would be considered Schedule I under the Federal Analogue Act if sold for human consumption.
O-Acetylpsilocin, being an ester of psilocin, is a class A drug in the UK under the Misuse of Drugs Act 1971.
O-Acetylpsilocin is illegal in Italy as it is an ester of a prohibited substance.Buy 4-Aco-DMT Online
The Riksdag added 4-AcO-DMT to Narcotic Drugs Punishments Act under swedish schedule I (“substances, plant materials and fungi which normally do not have medical use” ) as of January 25, 2017, published by Medical Products Agency (MPA) in regulation HSLF-FS 2017:1 listed as 4-acetoxi-N,N-dimetyltryptamin
O-Acetylpsilocin can be obtained by acetylation of psilocin under alkaline or strongly acidic conditions. It is, therefore, a semi-synthetic compound. It is believed to be a prodrug of psilocin, however, speculation that psilocetin may itself also be active exists. O-Acetylpsilocin is more resistant than psilocin to oxidation under basic conditions due to its acetoxy group. While O-acetylpsilocin is not well researched (sometimes viewed negatively as a research chemical, as opposed to psilocin and psilocybin), though it is not as difficult to produce as psilocybin. Due to their similar mechanism of action, this may further support ideas of O-acetylpsilocin possibly serving as an appropriate substitute to psilocybin for use in research of the effects psychedelic compounds in medicine.