Methamphetamine (Crystal Meth ) (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine.Methamphetamine properly refers to a specific chemical, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms. It is rarely prescribed over concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy. Dextromethamphetamine is a much stronger CNS stimulant than levomethamphetamine.
Both methamphetamine and dextromethamphetamine are illicitly trafficked and sold owing to their potential for recreational use. The highest prevalence of illegal methamphetamine use occurs in parts of Asia, Oceania, and in the United States, where racemic methamphetamine, levomethamphetamine, and dextromethamphetamine are classified as schedule II controlled substances. Levomethamphetamine is available as an over-the-counter (OTC) drug for use as an inhaled nasal decongestant in the United States. Internationally, the production, distribution, sale, and possession of methamphetamine is restricted or banned in many countries, due to its placement in schedule II of the United Nations Convention on Psychotropic Substances treaty. While dextromethamphetamine is a more potent drug, racemic methamphetamine is sometimes illicitly produced due to the relative ease of synthesis and limited availability of chemical precursors.
In low to moderate doses, methamphetamine can elevate mood, increase alertness, concentration and energy in fatigued individuals, reduce appetite, and promote weight loss. At very high doses, it can induce psychosis, breakdown of skeletal muscle, seizures and bleeding in the brain. Chronic high-dose use can precipitate unpredictable and rapid mood swings, stimulant psychosis (e.g., paranoia, hallucinations, delirium, and delusions) and violent behavior. Recreationally, methamphetamine’s ability to increase energy has been reported to lift mood and increase sexual desire to such an extent that users are able to engage in sexual activity continuously for several days. Methamphetamine is known to possess a high addiction liability (i.e., a high likelihood that long-term or high dose use will lead to compulsive drug use) and high dependence liability (i.e. a high likelihood that withdrawal symptoms will occur when methamphetamine use ceases). Heavy recreational use of methamphetamine may lead to a post-acute-withdrawal syndrome, which can persist for months beyond the typical withdrawal period. Unlike amphetamine, methamphetamine is neurotoxic to human midbrain dopaminergic neurons. It has also been shown to damage serotonin neurons in the CNS. This damage includes adverse changes in brain structure and function, such as reductions in grey matter volume in several brain regions and adverse changes in markers of metabolic integrity.
Methamphetamine belongs to the substituted phenethylamine and substituted amphetamine chemical classes. It is related to the other dimethylphenethylamines as a positional isomer of these compounds, which share the common chemical formula: C10H15N1.
Methamphetamine also known as “meth” or “crystal meth”. It exist in many forms which a listed below
There are three forms of methamphetamine:
Crystal commonly known as (‘ice’)
Powder also know (‘speed’)
Paste called (‘base’, ‘wet’ or ‘meth’).
Methamphetamine is an incredible, exceptionally addictive energizer that influences the focal sensory system. Otherwise called meth, blue, ice, and precious stone, among numerous different terms, it appears as a white, unscented, severe tasting crystalline powder that effectively breaks down in water or liquor. It is a white crystalline drug that people take by snorting it (inhaling through the nose), smoking it or injecting it with a needle. Some even take it orally, but all develop a strong desire to continue using it because the drug creates a false sense of happiness and well-being—a rush (strong feeling) of confidence, hyperactiveness and energy. One also experiences decreased appetite. These drug effects generally last from six to eight hours, but can last up to twenty-four hours.
How Take Methamphetamine
This drug can be taken in several ways, you can either:
Snort: Grunting methamphetamine powder is frequently by new clients. This can prompt harm of the sinus pits. A constant runny nose can be the outcome and proceeded with use may even prompt an opening being worn into the septum.
Smoking Methamphetamine : As of now, the most well-known strategy for manhandling meth is by smoking it, as indicated by the National Institute on Drug Abuse’s Community Epidemiology Work Group information. The hydrochloride salt of methamphetamine can be taken independent from anyone else without adding it to something different or change its structure. Right now or “ice” structure it shows up as blue-white rocks. Regularly, gem meth is smoked in a little glass pipe called a “woodwind.” . If you are searching for proof that somebody might be smoking meth, finding such a channel would be a piece of information.
Smoking meth can prompt the symptoms of “meth mouth,” with dry mouth and eroded teeth and gums. Meth regularly contains different fixings left from the illegal assembling process, which can have numerous impacts past those of the medication itself. Other than that you can test positive for meth after introduction to used smoke.
Injecting Methamphetamine: The powdered form of methamphetamine can be injected into the bloodstream. As with injecting any drug, this carries a high risk of blood-borne infections such as HIV, hepatitis C, and hepatitis B due to sharing needles
Methamphetamine by Pill or Ingestion : Methamphetamine was originally developed for medical use and administered in pill form. Users can still take meth in that way today, either with manufactured pills, homemade pills, or other means of ingesting the drug.
EFFECTS OF METHAMPHETAMINE
- Loss of appetite
- Increased heart rate, blood pressure, body temperature
- Dilation of pupils
- Disturbed sleep patterns
- Bizarre, erratic, sometimes violent behavior
- Hallucinations, hyperexcitability, irritability
- Panic and psychosis
- Convulsions, seizures and death from high doses
- Permanent damage to blood vessels of heart and brain, high blood pressure leading to heart attacks, strokes and death
- Liver, kidney and lung damage
- Destruction of tissues in nose if sniffed
- Respiratory (breathing) problems if smoked
- Infectious diseases and abscesses if injected
- Malnutrition, weight loss
- Severe tooth decay
- Disorientation, apathy, confused exhaustion
- Strong psychological dependence
- Damage to the brain similar to Alzheimer’s disease, stroke and epilepsy
In the United States, dextromethamphetamine hydrochloride, under the trade name Desoxyn, has been approved by the FDA for treating ADHD and obesity in both adults and children;however, the FDA also indicates that the limited therapeutic usefulness of methamphetamine should be weighed against the inherent risks associated with its use. Methamphetamine is sometimes prescribed off label for narcolepsy and idiopathic hypersomnia. In the United States, methamphetamine’s levorotary form is available in some over-the-counter (OTC) nasal decongestant products.
As methamphetamine is associated with a high potential for misuse, the drug is regulated under the Controlled Substances Act and is listed under Schedule II in the United States. Methamphetamine hydrochloride dispensed in the United States is required to include a boxed warning regarding its potential for recreational misuse and addiction liability.
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Crystal meth is a strong, highly addictive stimulant that influences the central anxious procedure. Also referred to as meth
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Those who are of the age of 6 and higher than and diagnosed with ADHD, then the dose should be 5mg as soon as or two times each day.
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Meth or ice is smoked by lights it with hearth and inhaling the smoke made by the burning things. The inhaled smoke produces the effects of substantial identical in mother nature to those created resulting from getting the drug from the powder variety.Crystal Meth
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