Psilocybe Mexicana


Quick Overview

The Psilocybe Mexicana can produce magic mushrooms and sclerotia (truffles).

Albert Hofmann isolated psilocybin and psilocin for the first time from the Mexicana species in 1958.

Both mushrooms and truffles can be consumed and are psychedelic.



Psilocybe Mexicana

Psilocybe mexicana are psychedelic mushroom which was known to be used by the natives of Central America and North America over 2,000 years ago. The native Aztecs referred to P. mexicana and other magic mushrooms as “teonanacatl,” which roughly translates to “flesh of the gods.”

  1. mexicana was also the species studied by Dr. Albert Hofmann which led to his discovery of the hallucinogenic compounds psilocybin and psilocin. Dr. Hofmann is also the same man who gained notoriety for consuming 32 different specimens of psilocybin mushrooms for the sake of science.

In his book, The Botany and Chemistry of Hallucinogens, he recounts his experience with Psilocybe mexicana as:

At the peak of my intoxication, about 1 ½ hours after ingestion of the mushrooms, the rush of interior pictures, mostly changing in shape and color, reached such an alarming degree that I feared I would be torn into this whirlpool of form and color and would dissolve. After about six hours, the dream came to an end. Subjectively, I had no idea how long this condition had lasted. I felt my return to everyday reality to be a happy return from a strange, fantastic but quite really experienced world into an old and familiar home.

Psilocybe Mexicana Identification

  1. mexicana’s cap is 1-2cm in diameter, conic with a small, protruding tip at the center. When young, the cap is an ocherous brown but takes on a straw color with age, sometimes with light bluish or greenish tones, indicating the parts where it may have been handled.

The gills beneath the cap are gray to purple brown with white edges. This moves downward towards the stem, or the stipe, which can be anywhere between 4 to 10 cm tall. It grows darker in areas where it is injured.

  1. mexicana produces dark purple brown spore prints as well as a strong, starchy flavor and smell. It also has the ability to produce sclerotia, a dormant form of the organism beneath the ground. It’s basically an underground mushroom. It provides protection from wildfires and other natural disasters.

Psilocybe Mexicana Habitat

In the wild, Psilocybe mexicana produces fruiting bodies from May to October. These mushrooms can grow solitarily or in small groups among moss located in roadsides, trails, meadows, cornfields, and the grassy areas bordering deciduous forests.

You have better chances of running into P. mexicana in areas elevated at 300 to 500 meters. Only three countries are known to produce this truffle-forming mushroom: Mexico, Costa Rice, and Guatemala.

Psilocybe Mexicana Effects

Psilocybe mexicana is perfect for beginners because it is one of the mildest psychedelic mushrooms on earth. You will start experiencing the effects of fresh magic truffles at a dose of 5 grams but these effects aren’t intense. From 10 grams onwards, a medium trip takes place, and a mind-blowing, strong trip starts at 15 grams.

Of course, the extent of how P. mexicana will affect you also depends on your own resistance, body weight, stomach contents, metabolism, and mood. If you haven’t tried magic mushrooms yet, it’s recommended you start out with a low dose of P. mexicana first.

You will feel the initial effects within 15 to 30 minutes. This is accompanied by mild visual alterations, slightly enhanced senses, and euphoria. It’s not uncommon to become more open-minded and accepting of new ideas and concepts. You will also lose track of time.

If you feel like you need to get more out of your P. mexicana trip, you can always consume more truffles. Rest assured that psilocybin from magic mushrooms and truffles do not cause a physical addiction, dependence, or overdose.

Psilocybe Mexicana Truffles Cultivation

Cultivating P. mexicana truffles is more economical, and makes you a more self-sufficient psychonaut. It’s also a simpler procedure but it will take time because magic truffles need longer to mature compared to magic mushrooms.

If you don’t have a magic truffle grow kit, you can start from scratch. This method may sound intimidating but this will give you more insight into the lifecycle of P. mexicana truffles. You will also be able to scale up or reduce your grow depending on your needs.

You will need the following supplies:

  • Spore syringe filled with Psilocybe mexicana spores
  • Grass seeds for your substrate
  • Grow bag with filter
  • Pressure cooker
  • Water


  1. Create a substrate using grass seeds. Mix ten parts grass seeds with 5 parts water.
  2. Sterilize the mixture. Put it in a grow bag, place it in a pressure cooker, and cook the contents at 15 psi for 1 hour. This will eliminate all organisms that will contaminate your grow and compete with the growing P. mexicana’s nutrition.
  3. Cool the substrate then inoculate it with your syringe. Shake the substrate to spread the spores all over it.
  4. Keep the mixture in a dark place with temperatures between 21 to 25 degrees Celsius.
  5. Wait for the mycelium to colonize the substrate. This will take up to a month.
  6. After the colonization period, you’ll need to wait just a little bit more. Leave the colonized substrate in the dark room and stop moving it to allow the development of hard, walnut-looking lumps – the truffles. It takes 3 to 4 months for these truffles to grow. The longer you leave them, the larger they become.

Psilocybe Mexicana Grow Kits

Spores vials are superior to the spore syringes in most fields. Get the best results when cultivating Jalisco P. mexicana magic mushrooms with this quality spore vial. Using spore vials will cause a higher success rate in the colonization and fruiting process.

Reasons to go Vial:

  • Longer shelf life than most spore syringes (2 years vs 6 months)
  • It’s easier to get ALL spores out of the container. Plastic they often charge syringes with static electricity, making the spores stick to them. Glass vials are never charged, so 100% of the spores will come out.
  • Works great with liquid culture growth media. We can prepare syringes with a unique solution, rendering any liquid culture medium unusable.
  • The spore vial solution has over a 1000 grow parts per milliliter, versus 500 g.p.p. ml or even less in most syringes.
  • Professional look and feel
  • Takes up less space
  • Easier to transport


  • 1x Glass Vial with 10ml Jalisco P. mexicana mexicana spore solution
  • 1x Sterile 10ml Syringe
  • 2x Alco Preps

Instructions to use a Jalisco P. mexicana spore vial

The vials have a cap with a circular rubber membrane. The needle of a syringe can pierce the rubber membrane, or septa, but will stop any airflow, micro organisms or anything else to go through by itself.

Shake the Jalisco P. mexicana spore vial vigorously to disperse the spores throughout the vial. Remove the protective stopper cap from the top of the vial and sterilize the septa with an alco prep. Unpack the sterile syringe and remove the protective cap from the needle. Insert the needle of the syringe through the septa.

The point of the needle should be submerged in the spore solution. Pull back the plunger of the syringe slowly so that the syringe will fill with spore solution. We need just 3 milliliter of spore solution to colonize 1 liter / 1.05 quart of substrate. After having filled the syringe with the required amount of spore solution, slowly take out the needle from the vial.

To proceed from here to the inoculation process, there are several methods to choose from:

Dropping the spore solution onto the substrate

After having prepared your own substrate or cakes, you can drop the Jalisco P. mexicana spore solution directly from the syringe onto this. Press the plunger slowly so that dropplets of spore solution will come out of the needle. Every dropplet that will be in contact with the substrate is a potential mycelium growth point. Spread out these dropplets over the substrate evenly to colonize the substrate mycelium.

Injection through injection ports

This is almost identical as dropping the spore solution onto the substrate. Open the injection port by pulling back the port protection cap. Use a alco prep to sterilize the injection port entry. Pierce the opening with the needle. Now drop the spore solution evenly over the substrate inside the spawn bag or grow box. After the Jalisco P. A Mexican spore solution is injected, remove the syringe and close the injection port with the port protection cap.

Liquid culture for faster colonization and stronger mycelium

When injecting the Jalisco P. mexicana spore solution in a ‘bath of nutrients’, such as the Liquid Culture Growth Medium, the spores will form into mycelium inside this liquid suspension. This is called liquid culture or LC for short. Liquid Culture Growth Medium itself can be used to inoculate substrate and cakes. Liquid culture growth medium has a higher success rate and will be much more reliable than trying to germinate the spores without the use of  LC. In short: Using LCs will increase the chance on mushrooms.

Note: The Liquid Culture Growth Medium will not work well with our spore syringes.

Study spores and research using a microscope

The wondrous world of the spores. Many of our customers are scientists, doing research on these differences in a homemade laboratory. After having prepared your microscope slide, drop some of the Jalisco P. mexicana spore solution on it. Cover the specimen with a microscope covering glass. The best magnification for Psilocybe mexicana and Panaeolus cyanescens spore research is a magnification of 1000x or higher.

The syringe and reusing it

After using the syringe to inoculate the substrate, cake, or LC  with Jalisco P. mexicana, you can reuse the empty syringe after you have sterilized the needle. We can do this with a spirit burner or lighter. Burn the needle by keeping it in the flame long enough to make it glow orange. Let it cool down before you insert the needle again. Instead of reusing one, you can also order a sterile needle separately.


Store the Jalisco P. mexicana vial in the refrigerator between 2°C – 8°C or 35°F – 46°F. Leave the ‘septa protecting stopper cap’ in place when storing the vial. After removing this protective cap, always sterilize the septa with an alco prep before you insert the syringe.

Jalisco P. mexicana spore vials can be stored this way for 2 years after leaving our warehouse.

Instructions Video












Additional information


1 Oz, 3 Oz, HP, 1 P

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